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sclerosis

noun

scle·​ro·​sis sklə-ˈrō-səs How to pronounce sclerosis (audio)
1
: pathological hardening of tissue especially from overgrowth of fibrous tissue or increase in interstitial tissue
also : a disease characterized by sclerosis
2
: an inability or reluctance to adapt or compromise
political sclerosis

Example Sentences

Recent Examples on the Web One culprit for permitting sclerosis is the National Environmental Policy Act (NEPA), a 1970 law that imposes environmental reviews. The Editorial Board, WSJ, 29 July 2022 Multiple sclerosis is a central nervous system disease that affects the brain and spinal cord. Beth Krietsch, SELF, 22 July 2022 Lawmakers would do well to advance policies that would cure the agency's sclerosis. Sally Pipes, Forbes, 18 July 2022 A year later, scientists reported that pathological TDP-43 was also present in the brains of people with Alzheimer’s disease and hippocampal sclerosis, a disease associated with pathological changes in the hippocampus. Diana Kwon, Scientific American, 13 July 2022 More widely, the failure will speak to the sclerosis of American governance. Robinson Meyer, The Atlantic, 15 June 2022 Multiple sclerosis is a potentially disabling disease of the brain and spinal cord. Ben Thomas | Bthomas@al.com, al, 27 May 2022 Robert Dallek, a historian and biographer of Lyndon B. Johnson, said such sclerosis had ebbed and flowed in the past. New York Times, 30 May 2022 Multiple sclerosis treatments, which cost between $8,000 and $11,000 in the mid-1990s, averaged $60,000 a year by 2015 and reached $80,000 by 2020. Billy Kenber, STAT, 14 May 2022 See More

Word History

Etymology

Middle English sclirosis tumor, from Medieval Latin, from Greek sklērōsis hardening, from sklēroun to harden, from sklēros

First Known Use

1846, in the meaning defined at sense 1

Time Traveler
The first known use of sclerosis was in 1846

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