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- crow's-feet 42
- perplexedness 15
- correspondence course 56
- pcp 42
- postage 367
- landform 110
- barefaced 66
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- anticipate 388
- sheikdom 12
- infuriated 51
- salaryman 18
- misstep 25
- rendering 47
- premium 118
- fave 69
- proliferating 25
- tittie 23
- Forceful 30
- seek 379
- FIERCE 27
- Bordeaux 25
- girlish 62
- turkmenistan 19
- anesthetist 72
- Devalue 107
- profoundly 84
- Bolshevik 23
- Editorial 75
- pay down 28
- a slice of the cake 51
- subaltern 20
- screw 404
- Eye-opener 44
- corruptible 51
- Literary 65
- devilment 66
- breeder 77
- Extricate 105
- Illicit 58
- Excellency 52
- peskier 15
- Intimidate 52
- zither 23
- now for 44
- glottides 10
- deserter 67
- creeper 59
- numerally 12
- eric 26
- polymer 23
- specific 386
- presweetened 12
- flow 412
- superfine 18
- stepdaughter 23
- vegetated 12
- barely 318
- governor general 37
- readmitted 12
- personable 101
- pull down 47
- Breaking 34
- byproduct 33
- natal 100
- on foot 20
- equestrian 63
- gadfly 63
- extortionate 43
- didjeridoo 25
- Las 23
- bolero 67
- catchphrase 73
- meagre 36
- hereditary 79
- competent 370
- uproarious 19
- priestly 27
- president 386
- containment 59
- resent 118
- Jobs 147
- pu 17
- pkwy 17
- summarization 127
- scrutinize 204
- noisier 15
- fool around 67
- pathogenesis 21
- colorist 73
- undershot 19
- Anxiously 31
- seaplane 26
- homogenize 24
- out of 44
- transformer 408
- inaccurate 123
- Passion 215
- cow 498
- disguise 423
- burlier 42
- Conserve 27
- mortuary 28
- Scrutinise 76
- Italic 76
- proofless 17
- micromanage 37
- subscript 19
- Inquire 131
- easier 29
- Sparingly 21
- weakening 17
- Barrier 26
- bass 89
- jicama 15
- doorknob 64
- cold war 75
- prostitution 28
- jute 26
- fop 72
- digerati 56
- beard 349
- Sicken 17
- kirk 30
- American football 59
- intelligible 88
- barbie 51
- sollar 15
- Determiners 28
- prewash 16
- farmstead 45
- neuralgia 36
- buddy 126
- Immobile 18
- bagful 103
- Define 138
- oi 23
- lilied 14
- unwonted 19
- ramrod 144
- Exploratory 136
- whilst 309
- domain 172
- compass 465
- you bet 24
- Turkmenistan 16
- traitor 375
- recur 77
- pertinent 299
- Whale 45
- refiner 99
- schematic 155
- chalk 409
- buzz-cut 27
- homing 44
- Horse 38
- paystub 116
- tombless 10
- implication 458
- ova 24
- pick up the bill 18
- sky 42
- diluteness 33
- protein paint 22
- dj 49
- destruction 369
- lm 19
- dig up 70
- jeweler 30
- militiaman 26
- smegma 17
- scanty 172
- litter 203
- cid 38
- recite 361
- Vividly 91
- sidewalk 47
- understaffed 22
- Synonyms 11
- prepare 408
- daycare 36
- Carve 53
- draftsmen 29
- head-scratcher 153
- cache 170
- Slayer 48
- Dissuade 43
- backgammon 104
- thunder 413
- amoebic 45
- sandbagged 13
- immunities 10
- coastwise 27
- providing 107
- coagulate 59
- TM 27
- Escape 93
- leakier 10
- ripple effect 51
- Tired 88
- custody 203
- curable 46
- payable 24
- stir up 33
- Disciplined 86
- ingratiating 26
- meticulosity 33
- crash helmet 59
- abused 52
- Household 134
- psychological 355
- Binge-watch 55
- crest 77
- uncharted 118
- compute 306
- Brunch 49
- salem 25
- region 452
- Merchandise 59
- stockinged 16
- on sale 32
- toils 11
- reincarnation 56
- tamboura 19
- haunted 97
- confabbed 26
- starkers 21
- agar 48
- interviews 11
- Constantly 78
- tbd 22
- Conceptual 38
- faze 79
- unworldly 18
- mummer 24
- promote 400
- surpass 146
- reformation 85
- reformist 16
- chockful 12
- dwindle 121
- indentures 13
- freak out 75
- sunup 26
- inauguration 189
- survival 373
- flex 120
- immortalize 127
- Misfortune 63
- factual 103
- Special 138
- barrier 390
- Would 115
- outreach 104
- impunities 11
- jalapeño 21
- roasted 38
- sappy 28
- manifestation 22
- purgatory 26
- ian 23
- directorship 48
- aah 66
- grab 196
- pieties 18
- Saudi Arabia 37
- food processor 75
- covey 62
- invention 355
- fiddle with 67
- reconfiguration 16
- literature 381
- yellowy 18
- attractively 103
- kilojoule 15
- centralise 49
- validate 69
- rwy 18
- THEFT 57
- carpeting 41
- Stamp 54
- empire 414
- brawl 189
- produce 412
- robot 353
- sq. 24
- superconduct 16
- irretrievable 148
- consistently 94
- dudgeon 70
- taut 52
- Regardless of 41
- girlie 68
- godhead 64
- flags 24
- penology 19
- take something into account 10
- disclosing 43
- unilaterally 104
- deflate 169
- tory 28
- hindrance 153
- back burner 75
- hegemonies 10
- Boundless 74
- physicist 383
- persuade 403
- vest 416
- Bounty 66
- peeved 23
- candy floss 36
- enviable 74
- frazzle 67
- hookup 17
- knack 34
- petrol 350
- liability 148
- way out 26
- liberation 359
- identifier 12
- thataway 12
- authorities 47
- Inquiry 47
- Import 126
- capacity 371
- used 408
- popularly 18
- ancestral 74
- downtick 36
- impersonation 90
- Rely 150
- gut 255
- inspiration 155
- shameful 46
- Subtitle 59
- nightshirt 22
- AIM 52
- mphil 23
- brickie 48
- tried 22
- participant 211
- steal 382
- socialising 33
- autopilot 76
- char 375
- viral marketing 50
- sauropod 21
- piddling 33
- biodegradable 97
- quintuplet 22
- cannily 55
- ye 26
- increased 101
- Proceed 184
- Agriculture 183
- obtrude 45
- particular 332
- Belongings 101
- recover 334
- zuni 19
- semitone 23
- facility 426
- assertive 68
- assertiveness 4
- vibrant 150
- Exponential 56
- hostages 15
- correspondent 363
- disinflation 49
- changeable 72
- suing 13
- Denounce 56
- heuristic 30
- Hitchhike 70
- dwight 21
- fashion victim 41
- Purposeful 95
- enhanced 42
- spaceman 25
- Function 120
- put away 40
- dozed 26
- charter school 11
- fiduciary 72
- insulate 135
- she'd 153
- Leisurely 30
- excursion 390
- ametabolism 19
- dpi 49
- spiritualism 23
- nonrestrictive 20
- citizen's arrest 51
- Newfoundland 41
- boat train 36
- pompous 120
- Feline 63
- scrunchy 11
- Jest 130
- refill 22
- Refund 51
- Obtrusive 120
- coordinated 108
- cl 52
- smallholding 28
- trivial 194
- Sport 143
- unshaken 25
- nesting 14
- digger 68
- Dairy 48
- Virginia 43
- torrent 380
- ASIDE 32
- laurier 48
- durable goods 46
- predate 134
- dislike 381
- dumpling 133
- dyed-in-the-wool 59
- deputization 31
- grade point average 47
- parataxis 20
- attach 456
- long johns 59
- agglomeration 70
- tutelage 21
- Situated 144
- floury 49
- Interference 44
- quits 27
- salvation 153
- tolerate 476
- prize 432
- pars 14
- nosh 29
- by and by 33
- contagious 172
- potty 32
- betel nut 31
- new york 47
- deprive 138
- bombed 64
- elmy 22
- acquittal 159
- intensively 9
- onrush 28
- Motivation 210
- citizen 367
- larval 26
- statin 22
- feisty 123
- dip 379
- disqualifies 36
- tweet 31
- jury-rig 103
- intervenient 18
- species 408
- ideologically 100
- exhausted 137
- Encode 30
- federated 38
- burst 366
- perspective 545
- saudi 19
- sloganeer 22
- chubby 92
- cozily 120
- yd. 24
- humdrum 120
- door-to-door 49
- capitulation 65
- sesotho 19
- cherry 340
- hoopoe 22
- handicraft 77
- pastries 14
- windsurfer 20
- print 382
- inwardly 71
- slink 161
- clinic 152
- Nob 62
- expel 375
- matchbox 17
- bambara 36
- chico 15
- compose 379
- tizzy 26
- State 181
- Accomplished 118
- moneylender 33
- cutes 12
- Willpower 50
- maya 20
- dives 42
- spires 19
- ultimately 329
- depoliticize 25
Example Sentences
Recent Examples on the Web This vacuole pushes the cell’s essential proteins, sugars and metabolites against its membrane, facilitating easier diffusion. 
Sumeet Kulkarni, Los Angeles Times, 23 June 2022 Depending on the density of the flock and speed of the predator, the starlings’ reactions can take many escape patterns, including flying outward to create a vacuole—an empty space. Lauryn Hill, Wired, 5 Feb. 2021 The central empty spaces are vacuoles, which get larger and larger as injured cells approach death. Sharon Begley, STAT, 3 May 2018 Unlike Thioploca and a related genus called Beggiatoa, it was not contained in a containment sac called a vacuole. Scientific American Blog Network, 21 Apr. 2017 In this slice of potato 1,000 times thinner than a Pringle, the red circles are vacuoles— Tom Conlon, WIRED, 23 Oct. 2007 As the ice evaporated and carbon dioxide built up in the surrounding air, the acidity increased, causing the pigments stored in tiny vacuoles, or bubbles in the petal’s outer cells, to shift from blue to pink. Joanna Klein, New York Times, 2 Mar. 2016 See More
Sumeet Kulkarni, Los Angeles Times, 23 June 2022 Depending on the density of the flock and speed of the predator, the starlings’ reactions can take many escape patterns, including flying outward to create a vacuole—an empty space. Lauryn Hill, Wired, 5 Feb. 2021 The central empty spaces are vacuoles, which get larger and larger as injured cells approach death. Sharon Begley, STAT, 3 May 2018 Unlike Thioploca and a related genus called Beggiatoa, it was not contained in a containment sac called a vacuole. Scientific American Blog Network, 21 Apr. 2017 In this slice of potato 1,000 times thinner than a Pringle, the red circles are vacuoles— Tom Conlon, WIRED, 23 Oct. 2007 As the ice evaporated and carbon dioxide built up in the surrounding air, the acidity increased, causing the pigments stored in tiny vacuoles, or bubbles in the petal’s outer cells, to shift from blue to pink. Joanna Klein, New York Times, 2 Mar. 2016 See More Word History
Etymology
borrowed from French, probably borrowed from New Latin vacuolum "little vacuum," from Medieval Latin vacuum vacuum entry 1 + Latin -olum, variant of -ulum -ule with stems ending in a vowel
First Known Use
1853, in the meaning defined at sense 1
Time Traveler
The first known use of vacuole was in 1853 Phrases Containing vacuole
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