These days, detoxify can mean to free (someone) from a substance addiction (and yes, it's the source of detox, a more recent word that also refers to getting drugs or alcohol out of a person's system). Originally, however, detoxification was something done to things rather than to people. In its earliest uses - from about 1905 - detoxify referred to the removal of poison, or of poisonous or damaging properties, from a harmful substance, or to the removal of poisonous or toxic substances from something contaminated (such as the bloodstream).The specific application to removing poison from an addict is relatively new, dating to the mid-20th century. Today, detoxify is also often used generally in reference to counteracting the activity or effect of anything harmful (such as propaganda).