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- APPEAL 101
- flamenco 104
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- REGARD 142
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- descendent 42
- Giggle 132
- bag 354
- ecosystem 100
- Radar 134
- cankery 45
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- flawed 159
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- eminently 112
- riverfront 74
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- kotwal 43
- pole 206
- passenger 518
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- prime mover 46
- thymus 56
- human 459
- deride 115
- fioriture 26
- deadpan 135
- serged 29
- penetrable 135
- icu 57
- junk food 92
- sooty 77
- informer 63
- greenhouse effect 137
- episcopal 110
- drop in 101
- Swoopy 17
- subpar 54
- Reuter 81
- afro-caribbean 71
- inclination 126
- corselet 37
- decorator 113
- chamois 120
- Transparent 119
- pique 96
- offprint 46
- TUC 44
- authorize 300
- Peaked 81
- depute 104
- Penultimate 49
- kurdish 49
- aerobatics 153
- fun 281
- embassador 41
- clear-felling 63
- mainer 54
- ltd 55
- Live up to 50
- Whopping 41
- full time 102
- falsify 195
- overoptimistic 45
- Incriminate 27
- Citizen 239
- outgun 67
- appearance 600
- wishes 33
- Boat 168
- whizzy 52
- saunter 93
- small 153
- dispatchers 42
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- Repatriate 16
- assoc. 51
- spill 500
- death toll 127
- biosphere 141
- hommock 45
- tramcar 61
- chop down 97
- baloney 125
- jetsam 88
- petrodollar 50
- brokerage 145
- plain 492
- sunlamp 82
- agroforester 30
- Menstrual 39
- Obvious 281
- detail 581
- Irreversible 81
- protozoon 64
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- Crowded 98
- peerlessness 26
- cash machine 88
- muggiest 28
- scrum 88
- balaclava 105
- economic 518
- granny 126
- Brine 31
- unleash 64
- ghat 80
- deontic 43
- album 146
- alone 491
- susceptibility 146
- Sea anemone 27
- knavish 59
- marcasite 43
- Months 54
- unlearned 60
- poet 460
- pomegranate 133
- Rev. 96
- charwoman 111
- look 353
- forecastle 67
- redefine 118
- hindquarter 39
- sick to your stomach 101
- pull away 42
- cesarean section 84
- mental 466
- Widespread 249
- Anomalous 83
- contrastive 104
- paraglide 60
- neighborhood 515
- outgrew 34
- burring 32
- orth- 37
- tailback 71
- Rectangular 88
- recently 459
- manoeuvres 33
- nightclub 96
- housefly 65
- Ghana 87
- lifeblood 59
- upturn 104
- Entrench 18
- Queen 118
- Fuck 172
- Inordinate 55
- tinged 36
- Frown 240
- Wait 37
- Memorize 154
- Diligence 59
- vga 52
- vixen 54
- blueprint 132
- serbia 66
- loiter 179
- stop 416
- wore 50
- sacrifice 598
- BUILD 114
- legitimacy 159
- devoicing 26
- area 664
- Close call 8
- smote 55
- crotchety 151
- fly ball 97
- Intellectually 53
- bridegroom 130
- degrading 120
- creolize 53
- Cortex 39
- graceless 113
- empire 528
- snob 145
- APPLY 103
- corker 105
- cía 84
- Corpse 140
- Commemorate 192
- Uphold 116
- duvet 128
- radiotherapy 75
- oases 67
- antiasthmatic 28
- irritated 254
- Detailed 89
- specification 220
- genealogize 70
- (as) blind as a bat 28
- Success 266
- Throughout 184
- Spiral 64
- basinal 49
- bride 139
- variance 113
- fleet 510
- dysfunctional 155
- Note 139
- jimmy 63
- underweight 190
- virology 53
- Heaven 148
- winder 55
- sports 130
- lettuce 188
- bullhorn 124
- airplane 556
- Crest 123
- hand luggage 90
- multiparty 56
- puddle 51
- chairperson 168
- phonic 84
- Verge 226
- Area 180
- brained 74
- Portable 150
- waged 81
- deserts 84
- tatters 71
- libelous 163
- fomentation 53
- gunslinger 109
- widthwise 41
- idaho 55
- hug 241
- inhere 61
- thirteenth 43
- health care 184
- lose out 93
- Navajo 66
- coda 125
- dialectic 132
- mushrooming 42
- automatic pilot 94
- defect 570
- aquilinity 41
- champagne 108
- remorseful 69
- Alzheimer 65
- Flourish 137
- Inefficient 51
- ectomorph 45
- destructive 464
- Entice 33
- fruity 154
- genius 497
- death duty 85
- intrench 39
- tinker 93
- skyrocket 227
- acclimated 60
- viscount 74
- plateaux 29
- unflappable 45
- Groove 148
- funicular 115
- costly 483
- pollinator 62
- Spoilage 31
- Harlequin 49
- stagecraft 46
- prologue 65
- pregnancy 132
- rif 46
- denitrification 49
- droppings 76
- abundance 210
- chunky 252
- Solace 19
- palmy 103
- cobnut 71
- sarin 50
- Fold 78
- known 71
- chorus 271
- Lug 23
- Endeavour 92
- on the loose 55
- bantu 69
- replace 517
- raik 50
- Rule 211
- civies 34
- Formerly 153
- Quota 70
- Indictment 209
- brownstone 108
- An 176
- muckhill 11
- interference 557
- ease 682
- won 188
- Script 250
- Depreciate 213
- undeniably 47
- transcontinental 58
- duffer 110
- ringleader 54
- sobbingly 34
- excludable 65
- button 509
- kick 492
- Oriental 77
- battery 521
- discourteous 111
- changing 50
- North Dakota 15
- gawk 122
- baby boom 100
- shoulder 587
- Hemmed 33
- Advisories 47
- tankful 37
- Preempt 169
- braeburn 34
- Adorable 14
- devalue 270
- heliport 70
- Codependent 15
- Montana 57
- arachnid 100
- greenhorn 99
- dishonorable 127
- midland 71
- Pained 124
- Ore 176
- come at 112
- High 251
- GRIT 103
- Wood 153
- lag 490
- Boy 154
- adapter 231
- Nation 261
- naivete 61
- matey 171
- Tupperware 59
- Ties 42
- circumflex 145
- enlarged 56
- Solar 159
- officious 83
- automata 72
- roadhouse 72
- supporter 76
- presentational 52
- bright 292
- noble 462
- HORRIFY 63
- relent 226
- wilds 28
- doss house 83
- teammate 102
- cell 496
- housebreaking 77
- missive 94
- Ignite 96
- half hour 119
- Silk 129
- Doubtful 48
- revue 120
- revuist 36
- countermove 74
- biden 37
- Resignation 85
- Ambience 67
- lunier 32
- ghastliest 54
- Container 172
- collegiate 176
- perturb 108
- horrifying 83
- twat 184
- Brick 111
- Weakness 172
- let 237
- Employer 218
- Pandemonium 76
- Fairy tale 69
- Dynamic 215
- Chintz 86
- hexa- 36
- anna 46
- excuse 270
- dodge 158
- decade 524
- comment 610
- Go by 52
- abalone 196
- matzoh 36
- northern 468
- Wry 120
- unfitness 105
- wontless 39
- ballpoint pen 128
- drop 532
- poodle 50
- gaggle 107
- ganglion 181
- infant 530
- underclass 52
- acclimate 132
- swingeing 160
- flat foot 85
- blameworthy 159
- specificity 167
- rubbernecker 58
- exact 403
- aphoristically 61
- ravel 169
- INVOLVE 105
- devanagari 59
- blind 475
- cackle 248
- blue jeans 87
- fall 517
- emphysema 123
- Theoretical 190
- immerse 352
- Keen 236
- citywide 104
- Tennis 119
- volt 590
- strategy 540
- mince 138
- malign 86
- bluebell 100
- citadel 109
- deceased 149
- ana 57
- Div. 38
- doglike 48
- normanize 43
- obstinate 117
- bam 73
- Constantly 128
- cloven hoof 106
- Wi-fi 42
- slender 538
- aero- 149
- Prolific 30
- Consequence 183
- colonist 140
- human geography 49
- Rude 104
- rejuvenation 159
- mesophyll 32
- bake-off 60
- length 526
- driven 119
- Prey 146
- courtliest 41
- takeout 176
- realize 620
- veena 26
- marshy 92
- delphically 26
- jubilant 80
- Friction 29
- happy 286
- longe 39
- AIRTIGHT 90
- smack of 54
- lymphatic 59
- -cide 44
- Edification 4
- grainy 151
- sylph 71
- opportunity 573
- charlotte 113
- helipad 52
- go at 70
- leechee 40
- Intruder 96
- Segment 61
- bmoc 71
- birchen 47
- finisher 84
- cooperation 212
- connected 114
- Tint 91
- Dodge 55
- jacuzzi 57
- mushroomer 39
- bonhomie 108
- Zigzag 222
efficacious
adjective
ef·fi·ca·cious ˌe-fə-ˈkā-shəs 
efficaciously adverb
efficaciousness noun
Did you know?
Effective, effectual, and efficient are synonyms of efficacious, but each of these words has a slightly different connotation. Efficacious suggests possession of a special quality or virtue that makes it possible to achieve a result ("a detergent that is efficacious in removing grease"). Effective stresses the power to produce or the actual production of a particular effect ("an effective rebuttal"), while effectual suggests the accomplishment of a desired result, especially as viewed after the fact ("measures taken to reduce underage drinking have proved effectual"). The last synonym, efficient, implies an acting or potential for acting that avoids loss or waste of energy ("an efficient small car").
Example Sentences
taking a cookie break while studying is one of the most efficacious ways of rejuvenating the mind that I have ever discovered
Recent Examples on the Web Over decades, UFAs have demonstrated their value by accelerating patients’ access to safe and efficacious medicines. 
Wayne Winegarden, Forbes, 15 June 2022 Seriously, who can say no to efficacious clean concealers and foundations? Kiana Murden, Vogue, 13 June 2022 Conversations on access and successfully treating psychiatric diagnoses often return to the question of efficacious medicines. Kathleen Frazier, Variety, 20 May 2022 Though the idea of the best clean concealers might conjure up depictions of serum-like dewy makeup formulas, Lawless’s concealer proves that even skin-friendly offerings can deliver an efficacious matte finish. Kiana Murden, Vogue, 18 May 2022 L'Occitane Known for botanical scents and pampering textures, L'Occitane's skincare and haircare products have also been multiple time GH Sustainability Award winners for their efficacious formulations and thoughtful, minimal waste packaging. April Franzino, Good Housekeeping, 28 Apr. 2022 The two-dose regimen didn’t prove as efficacious in protecting the youngest children from infection and disease, especially against the Omicron variant, as health officials had hoped. Alice Park, Time, 23 Mar. 2022 The cutting-edge Swiss skincare brand is famous for their impressively efficacious formulas and this assortment turns back the clock in style. Celia Shatzman, Forbes, 5 Nov. 2021 Because mRNA vaccines like Pfizer and Moderna need to be kept cold and their global supply is sparse, medical authorities instead used less efficacious but easier to transport vaccines like Sinovac, Johnson & Johnson and AstraZeneca. USA Today, 20 Mar. 2022 See More
Wayne Winegarden, Forbes, 15 June 2022 Seriously, who can say no to efficacious clean concealers and foundations? Kiana Murden, Vogue, 13 June 2022 Conversations on access and successfully treating psychiatric diagnoses often return to the question of efficacious medicines. Kathleen Frazier, Variety, 20 May 2022 Though the idea of the best clean concealers might conjure up depictions of serum-like dewy makeup formulas, Lawless’s concealer proves that even skin-friendly offerings can deliver an efficacious matte finish. Kiana Murden, Vogue, 18 May 2022 L'Occitane Known for botanical scents and pampering textures, L'Occitane's skincare and haircare products have also been multiple time GH Sustainability Award winners for their efficacious formulations and thoughtful, minimal waste packaging. April Franzino, Good Housekeeping, 28 Apr. 2022 The two-dose regimen didn’t prove as efficacious in protecting the youngest children from infection and disease, especially against the Omicron variant, as health officials had hoped. Alice Park, Time, 23 Mar. 2022 The cutting-edge Swiss skincare brand is famous for their impressively efficacious formulas and this assortment turns back the clock in style. Celia Shatzman, Forbes, 5 Nov. 2021 Because mRNA vaccines like Pfizer and Moderna need to be kept cold and their global supply is sparse, medical authorities instead used less efficacious but easier to transport vaccines like Sinovac, Johnson & Johnson and AstraZeneca. USA Today, 20 Mar. 2022 See More Word History
Etymology
borrowed from Middle French efficace "effective" or its source Latin efficāc-, efficāx "capable of fulfilling a function, effective" (from efficere "to make, bring about, produce, carry out" + -āc-, -āx, deverbal suffix denoting habitual or successful performance) + -ious — more at effect entry 1, audacious
First Known Use
1528, in the meaning defined above
Time Traveler
The first known use of efficacious was in 1528 👨🏻🏫 Mr. Ng 韋氏詞典 📚 – mw.mister5️⃣.net
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