: injury or death of tissue (as of the heart or lungs) resulting from inadequate blood supply especially as a result of obstruction of the local circulation by a thrombus or embolus: the process of forming an infarct
In myocardial infarction a coronary artery becomes obstructed and this leads to irreversible damage and necrosis of the heart tissue. Nicholas C. Price et al.
When dural sinuses are thrombosed, cortical and deep venous cerebral drainage is impaired, which can lead to infarction of the involved cerebral territories. Douglas J. Quint