: in a state of extreme physical or nervous fatigue and agitation
So relentlessly did my partner and I spring into our work throughout the week that by Saturday night we were frazzled wrecks. Jack London
A frazzled looking housefrau [=hausfrau], clutching a toilet scrub brush in one hand and the fist of a wailing toddler in the other, confronted me with a look of pure exasperation. Paul Di Filippo
She seems relaxed, breathing evenly; there's nothing here to get her frazzled. Bob Ottum
2
: damaged or weakened by strain or agitation : frayed