We don't know who first clutched his or her tummy and called the affliction "collywobbles," but we do know the word's earliest print appearance dates from around 1823. We also know that the word probably came about through a process called "folk etymology." In that process, unusual words are transformed to make them look or sound like other, more familiar words. Collywobbles is believed to be a friendlier-sounding transformation of cholera morbus (the New Latin term for the disease cholera) that was influenced by the words colic and wobble.