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- dwell 298
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- frenzied 110
- fidget 162
- command 507
- Delivery 213
- feeble 441
- speaker 539
- disclaimer 113
- propulsion 98
- BUREAU 65
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- regard 579
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- bodywork 87
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- Stem 196
- innovations 44
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- failure 535
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- filamentous 67
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- aide-de-camp 80
- serpent 58
- arrive 263
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- canary yellow 60
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- bowl 543
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- beyond 472
- creamery 104
- soundproof 75
- gusto 118
- growl 126
- lag 484
- curl up 100
- grown-up 223
- vessel 535
- windshield 198
- Plane 37
- wager 65
- greet 539
- gregariousness 98
- columnist 113
- candlewick 63
- manifest 174
- ground rent 81
- cite 284
- Rephrase 60
- disparage 195
- straitjacket 55
- scourer 55
- trainer 188
- rotate 514
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- stool 474
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- cook 218
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- Apt 92
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- obliged 186
- responsible 505
- left field 57
- dominica 77
- anathema 116
- enforce 559
- rain check 63
- attack 486
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- esker 61
- antipasto 114
- guardhouse 108
- rough it 49
- opulent 160
- kurta 54
- reliability 482
- chill 508
- insinuate 82
- alarm 499
- significance 506
- Modern 177
- Tedious 125
- flop 303
- Gratitude 93
- Lettuce 124
- unusual 577
- headrest 75
- cardiac 109
- carnet 54
- executive order 96
- silky 77
- assignment 469
- BIO 109
- martyr 343
- knead 62
- flatus 35
- Qualify 249
- landlocked 158
- myopic 110
- Utilisation 79
- bowel 462
- pansexual 47
- conductive 158
- tremble 628
- editor 503
- well-documented 92
- warlord 70
- give in 134
- fearful 560
- categories 42
- rag 541
- retain 586
- intertextual 32
- Fit 202
- guidebook 156
- miscarry 84
- tallboy 42
- lambaste 77
- tote 127
- abrade 97
- on call 56
- Photographs 64
- unwind 168
- madling 37
- tenured 177
- peaceful 575
- Cataract 10
- philadelphia 74
- greening 117
- Distinct 218
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- hire 517
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- sheila 61
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- judgement 376
- impassive 141
- supposed 204
- Landscape 263
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- acquired taste 82
- heartbreaking 75
- dinghy 257
- occupier 55
- birth 521
- selvedge 39
- Embed 66
- glowing 207
- Crushing 121
- third 310
- oboe 91
- gelled 53
- vr 99
- Eccentric 85
- faint 585
- motherboard 69
- correction 532
- coronary 136
- downtrodden 107
- get together 102
- affirm 181
- whichever 427
- as luck would have it 28
- Unconscious 222
- artifact 149
- restriction 531
- dogsled 72
- alternate 120
- hoist 77
- verify 557
- dioxin 101
- Buy 168
- Dullness 60
- centerfold 113
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- necessarily 462
- repetitious 94
- deceptively 81
- Overtly 92
- Gluten 77
- Cusp 121
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- aguish 30
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- shit 205
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- untenderly 44
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- southbound 55
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- Void 175
- anathemata 35
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- forsaken 96
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- cosmetic 171
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- Cuts 36
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- ostracize 99
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- rune 65
- tamper 72
- Nauseating 183
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- Ho 101
- Persistence 81
- wording 65
- heterodox 186
- website 228
- what's up? 99
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- reimburse 310
- FOMO 76
- overbridge 40
- Subtly 67
- blueprint 128
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- bandy 149
- craft 540
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- outwards 312
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- Flex 95
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- resentful 111
- underwear 95
- fraudfully 30
- anemic 150
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- dry 339
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- matriculant 32
- octahedra 27
- cabana 73
- lanolin 52
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- Afloat 186
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- mongolism 45
- genome 97
- shandy 75
- Snippet 33
- numerical 55
- flavor 295
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- Gossip 101
- what's up 35
- SCENT 134
- turnoff 126
- Clue 208
- gremlin 114
- pin down 58
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- what 287
- Risk 338
- Martyr 114
- succeed 492
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- witheringly 24
- Quartet 163
- rife 85
- wrist 511
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- irs 86
- marginalize 80
- accessibilities 7
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- hypo- 42
- carryall 98
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- dive into 54
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- article 520
- setting 774
- causeway 97
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- anode 123
- Favor 105
- lamb 520
- upgrade 231
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- surround 584
- forward-looking 84
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- slight 548
- dragoon 108
- booze 170
- correctional 126
- begonia 96
- Certitude 166
- claustrophobia 124
- mark up 67
- gofer 93
- stand-up 28
- photographer 228
- shiver 536
- superscript 53
- legalism 35
- delightless 50
- Scenery 182
- manual 643
- cross-training 49
- tycoon 67
- carryout 144
- dropkick 89
- think back 43
- oenology 39
- Innumerable 137
- craftspeople 89
- cereal 158
- woodpile 67
- Unorthodox 139
- escapee 74
- card 184
- ghettoize 120
- customers 56
- detainee 92
- Untouched 108
- belt 521
- imperil 191
- kuwait 66
- invalidate 72
- solidity 95
- Compassionate 182
- sufficient 567
- uncharacteristic 121
- Wasp 167
- easy 325
- snivel 85
- stablemen 30
- Beach 165
- course 660
- J 72
- pathology 148
- groggy 112
- needless to say 67
- Smash 121
- infinitesimal 143
- Advisor 78
- change up 88
- Finished 33
- culture 492
- effectiveness 70
- Maximum 15
- Prestige 232
- deserving 128
- hobo 197
Down syndrome
noun
variants or Down's syndrome
: a congenital condition characterized especially by developmental delays, usually mild to moderate impairment in cognitive functioning, short stature, upward slanting eyes, a flattened nasal bridge, broad hands with short fingers, decreased muscle tone, and by trisomy of the human chromosome numbered 21
called also trisomy 21
Word History
Etymology
J. L. H. Down †1896 English physician
First Known Use
1961, in the meaning defined above
Time Traveler
The first known use of Down syndrome was in 1961 👨🏻🏫 Mr. Ng 韋氏詞典 📚 – mw.mister5️⃣.net
切換為繁體中文