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- Rosemary 94
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- overdone 3
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- Lib 124
- demand 354
- gantlet 54
- crossing 160
- jackstraw 2
- Invoke 119
- Inter 118
- Inspired 136
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- Glance 158
- Gender 135
- Furnace 105
- Fundamentally 99
- Fulfill 108
- Fulfil 84
- Abstract 133
- Foster 146
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- Glossary 51
- Establishment 117
- agitato 4
- Enroll 99
- call upon 30
- Enrol 61
- Active 152
- Done 113
- Depict 120
- Border 128
- Bookshelf 83
- favoured 104
- Accumulate 138
- ankle 339
- phraseology 6
- dock 294
- blood group 45
- blood brother 60
- Swim 55
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- ischemia 3
- declaratory 64
- statutory 134
- distinct 378
- dialling code 24
- fettling 3
- disingenuous 55
- acceleratingly 4
- oath 158
- abstractness 6
- hubcap 3
- disleaf 3
- crevassed 5
- cirrhosis 44
- bug-eyed 34
- hesitate 325
- Keen 141
- guide dog 40
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- insolation 3
- alarm 328
- inkling 40
- dairy 269
- armories 17
- nutty 92
- calliper 32
- dressing-down 40
- attractant 92
- floribunda 2
- Exhale 96
- colliery 48
- fratricidal 48
- ankylosis 5
- drifter 114
- resistant 266
- surplus 361
- tail off 57
- uncommon 179
- photochemical 4
- cockney 35
- dinkier 22
- stipulation 130
- Late 25
- attractingly 5
- industrialize 286
- Outbreak 132
- Stasis 106
- butter 337
- creased 92
- certified 119
- Suffer 135
- deteriorate 146
- heathen 3
- ja 3
- mellifluous 63
- Prevention 142
- avoid 531
- Pygmy 14
- gum 299
- misspend 3
- ignominies 3
- testy 128
- Goat 89
- attainable 56
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- colony 316
- lacunate 2
- Label 122
- multicolour 2
- scream 314
- commercialise 79
- system 386
- afficionado 1
- oke 4
- step on someone's toes 33
- salty 123
- glorification 35
- epicenter 137
- dubbin 2
- pursuant 74
- pigsties 3
- Boxing 38
- classy 88
- greenflies 24
- foothold 164
- fantasy 315
- dismayful 3
- theorise 43
- alkaloid 30
- wherever 332
- jest 4
- convincing 147
- Alike 16
- pesach 4
- safe 298
- conceptualize 130
- overview 5
- beheadal 2
- Vary 53
- externality 6
- cherub 50
- patting 2
- betook 2
- martyr 219
- Phase 128
- handbrake 4
- invention 297
- crushing 38
- conflicted 115
- jig 1
- returning 47
- Function 95
- Translate 180
- automaker 48
- fondu 2
- estonian 26
- outburst 182
- corr 2
- Chain 168
- Engineer 129
- week 112
- chase 320
- distaff 55
- calendar 315
- porter 313
- Precaution 32
- gunsight 4
- bully 163
- macroscopic 47
- nanosecond 5
- vagabond 150
- cuisinier 4
- bolt 303
- crackhead 104
- whirl 343
- sleeve 465
- barrel 330
- penta- 3
- Isolated 139
- lutheran 4
- ear 145
- Unbearable 124
- free will 36
- geomagnetism 3
- inserted 3
- brush 140
- Unevenly 75
- Speculate 150
- Slumber 114
- ghostwrite 56
- Ripple 140
- case 212
- bare 292
- gasworks 57
- Outnumber 126
- Adaptation 106
- Knob 116
- Intuition 147
- deficiency 84
- Imperative 140
- seeking 32
- Hush 115
- Hum 97
- Hassle 125
- buddies 20
- Drought 86
- Diversion 134
- Decent 165
- etch 63
- Cynical 135
- Culprit 168
- Cease 125
- detainee 40
- limbo 4
- apply 375
- gloomy 356
- woodwork 159
- merchantability 2
- Music 131
- violation 104
- vine 290
- vibe 161
- vacillate 198
- transportation 296
- transistor 276
- precaution 333
- torn 119
- terminus 117
- lusty 2
- teenager 299
- ido 1
- tantamount 138
- tactlessness 114
- acid test 34
- farm out 34
- tactlessly 130
- tactless 177
- disarm 50
- leaded 3
- swarm 332
- suspiciously 88
- surveyor 132
- strainer 115
- Discreet 98
- academical 1
- largely 227
- storey 260
- stately 143
- distrust 46
- stab 298
- squat 129
- squalid 153
- intently 42
- sphincter 81
- spectrum 169
- scrubby 118
- oncology 5
- scrubber 134
- Disapprove 135
- scrub 131
- scrabble 130
- rouse 293
- floodplain 47
- repent 352
- remuneration 204
- overlier 4
- pharisaism 4
- receptacle 98
- frayed 39
- sheet 397
- railing 132
- ammeter 5
- coot 43
- urbanize 61
- profess 101
- charger 52
- prevailing 85
- zebra 280
- prestigious 136
- gaiety 50
- precariousness 124
- vapour 252
- precariously 124
- precarious 116
- Corps 122
- practiced 162
- citrus 87
- potbelly 71
- pollinate 100
- loveliest 3
- Choreographer 54
- polarity 121
- polarize 144
- diphtheria 69
- butterfingered 32
- polarization 95
- latency 4
- mixer 1
- iterate 57
- polar 124
- plaintive 72
- herdsmen 3
- perspective 475
- perfunctory 81
- Continuous 39
- opine 101
- sweep 309
- chin-up 35
- occurrence 324
- nascent 93
- curiosity 339
- myriad 90
- memorandum 274
- matrimony 112
- matrimonial 110
- loophole 91
- lineup 177
- linen 299
- knackered 94
- Ukrainian 71
- ineligible 123
- inclusion 117
- pachydermal 2
- overboard 73
- ignorantly 71
- prolonged 23
- bittersweetness 14
- ignorance 141
- revival 39
- ignoramus 100
- revenue 307
- arousal 118
- grandiose 106
- habitat 147
- chickweed 31
- mg 5
- gale 146
- Rap 36
- bilberry 37
- fussily 82
- lamed 5
- fraught 107
- agleam 4
- fella 101
- feedback 366
- kerbside 57
- falter 115
- explicit 173
- Apparently 84
- encroach 119
- inwardness 3
- emergence 207
- dynamic 298
- sold 32
- Surname 123
- drivel 108
- belt 322
- drain 320
- lodge 274
- bahadur 6
- downtown 106
- complication 146
- determinedly 78
- hula 5
- tree 163
- reconditioned 33
- custody 174
- lankier 3
- dyke 44
- curbside 155
- his 2
- credence 116
- creaky 122
- cheep 49
- Wishful 21
- contaminate 115
- combat 244
- forsaken 59
- coastal 845
- buy into 27
- chunky 174
- capitalization 136
- blazon 47
- stay 77
- crow 367
- bollard 42
- chimney 293
- pasteurizer 4
- check-in 132
- jackaroo 3
- champion 321
- cave-in 161
- back 233
- carpenter 287
- classifier 3
- gateman 22
- guesswork 54
- bunny 132
- brunt 131
- practise 224
- bare-bones 30
- perquisite 4
- blossom 324
- metalled 2
- Automatic 25
- cellar 300
- gusto 52
- ampere 271
- whisky 234
- wastewater 69
- vindication 108
- certain 306
- crank 35
- townie 101
- tedious 315
- hdmi 2
- suppression 156
- oceanfront 5
- solidarity 121
- pigeon 288
- rot 331
- depository 61
- practicable 319
- hospital 104
- -cy 30
- lieu 103
- lewd 95
- internship 81
- dispassionately 32
- Store 48
- induct 109
- inclINE 94
- Vent 96
- imperial 95
- humidity 111
- alienable 6
- hiatus 119
- hearten 89
- orchidology 3
- haze 138
- gourmet 102
- guidebook 94
- SILO 80
- advisable 335
- groundswell 89
- Inferences 20
- reclaim 158
- goat 314
- giddy 94
- Restraint 120
- geometry 336
- freehand 80
- Decorate 109
- foster 132
- fdic 5
- betaken 3
- Necessary 122
- subsidise 86
- Admiring 65
- intercession 125
- beetler 5
- taxpayer 59
- midlands 3
- hoist 1
- mending 3
- tarnish 182
- oreg 3
- Mediterranean 229
- exploit 368
- children 45
- partial 336
- stitch 320
- despisable 5
- crag 47
- company 192
- makeable 3
- army 345
- ditz 4
- surfeit 55
- eight 94
- friendship 74
- beetle-browed 30
- paralinguistic 4
- equinity 3
- Assignment 115
- resource 345
- outermost 3
- attend 358
- parasitize 3
- unsightly 48
- Epidemic 26
substance
2 ENTRIES FOUND:
plural substances
plural substances
Learner's definition of SUBSTANCE
1
[count]
a : a material of a particular kind物质；物品
- chemical/toxic/hazardous/dangerous substances化学/有毒/有害/危险物质
- The pancreas secretes a substance called insulin.胰腺分泌一种叫胰岛素的物质。
- The floor was covered with a white, powdery substance that turned out to be flour.地板上撒满的白色粉末状物质原来是面粉。
b : a drug that is considered harmful and whose use is controlled by law or made illegal（有害）药物
- heroin and other illegal substances海洛因和其他非法药物
- He had a history of substance abuse.他有嗜毒史。
- Codeine is a controlled substance. [=a drug that you need permission from a doctor to use]可待因是一种管制药物。
2
[noncount]
a : the quality of being meaningful, useful, or important实质；真正的意义；内涵
- matters of substance实质性问题
- When has he ever said anything of substance?他什么时候说过任何有意义的话？
- The book lacks substance.这本书内容空洞。
b : the quality of being true or believable真实性；可信性
- These rumors have no substance. = These rumors are without substance. [=these rumors are not true]这些谣言没有可信度。
- The results of the study give substance to their theory.研究成果证明了他们理论的正确性。
3
[noncount] : the most basic or necessary part or quality of something : essence主旨；要义
- the substance of my argument本人论点的要义
- These two books differ in both style and substance. [=content]这两本书在风格和内容上都截然不同。
- He stated, in substance [=in essence, essentially], that it is not his fault and he will not pay for damages.他所说的中心意思就是，这并不是他的错，他也不会赔偿任何损失。
a man/woman/person of substance
literary : a person who is rich and powerful有钱有势的人
- She married a man of substance.她嫁给了一个有钱有势的大人物。
sum and substance
substance
noun
sub·stance ˈsəb-stən(t)s 
1
a
: essential nature : essence
b
: a fundamental or characteristic part or quality
c
Christian Science : god sense 1b
2
a
: ultimate reality that underlies all outward manifestations and change
b
: practical importance : meaning, usefulness
Synonyms
Example Sentences
The pancreas secretes a substance called insulin. The floor was covered with a white, powdery substance that turned out to be flour. heroin and other illegal substances He had a history of substance abuse. When has he ever said anything of substance? The results of the study give substance to their theory. the substance of my argument See More
Recent Examples on the Web The county also promised to establish 300 additional substance use and mental health beds, according to a copy of the term sheet. 
Benjamin Oreskes, Los Angeles Times, 12 Sep. 2022 Her mother, Crystal Sorey, and father had substance abuse issues, the agency said. Marlene Lenthang, NBC News, 9 Sep. 2022 At the same time, the voices of both people who use drugs and people with substance-use disorders are absent from the chapter. Melissa Gira Grant, The New Republic, 6 Sep. 2022 One doctor who signed the letter, Stephanie Pierce, is the medical director of a clinic for pregnant women with substance-use disorders at the University of Oklahoma Health Sciences Center. Cary Aspinwall, al, 1 Sep. 2022 One doctor who signed the letter, Stephanie Pierce, is the medical director of a clinic for pregnant women with substance-use disorders at the University of Oklahoma Health Sciences Center. Amy Yurkanin, Washington Post, 1 Sep. 2022 However, the resident says Clenney’s substance use caused her demeanor to change. Andrea Marks, Rolling Stone, 26 Aug. 2022 According to a 2020 report from the homeless services agency, more than 14,000 unhoused people in the county have serious mental illnesses and more than 15,000 are grappling with substance abuse issues. Nick Watt, CNN, 24 Aug. 2022 Provost cited Renfro’s fear of them, substance abuse issues and a difficult childhood involving an alcoholic parent, an ADHD diagnosis at the age of 5, and exposure to domestic violence. Zaz Hollander, Anchorage Daily News, 18 Aug. 2022 See More
Benjamin Oreskes, Los Angeles Times, 12 Sep. 2022 Her mother, Crystal Sorey, and father had substance abuse issues, the agency said. Marlene Lenthang, NBC News, 9 Sep. 2022 At the same time, the voices of both people who use drugs and people with substance-use disorders are absent from the chapter. Melissa Gira Grant, The New Republic, 6 Sep. 2022 One doctor who signed the letter, Stephanie Pierce, is the medical director of a clinic for pregnant women with substance-use disorders at the University of Oklahoma Health Sciences Center. Cary Aspinwall, al, 1 Sep. 2022 One doctor who signed the letter, Stephanie Pierce, is the medical director of a clinic for pregnant women with substance-use disorders at the University of Oklahoma Health Sciences Center. Amy Yurkanin, Washington Post, 1 Sep. 2022 However, the resident says Clenney’s substance use caused her demeanor to change. Andrea Marks, Rolling Stone, 26 Aug. 2022 According to a 2020 report from the homeless services agency, more than 14,000 unhoused people in the county have serious mental illnesses and more than 15,000 are grappling with substance abuse issues. Nick Watt, CNN, 24 Aug. 2022 Provost cited Renfro’s fear of them, substance abuse issues and a difficult childhood involving an alcoholic parent, an ADHD diagnosis at the age of 5, and exposure to domestic violence. Zaz Hollander, Anchorage Daily News, 18 Aug. 2022 See More Word History
Etymology
Middle English, from Anglo-French, from Latin substantia, from substant-, substans, present participle of substare to stand under, from sub- + stare to stand — more at stand
First Known Use
14th century, in the meaning defined at sense 1a
Time Traveler
The first known use of substance was in the 14th century Phrases Containing substance
noun¹
noun²
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