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- suffocate 118
- transport 527
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- travel light 34
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- nosy 110
- navy blue 123
- inborn 103
- jihadi 44
- colorful 232
- pt 79
- dumbfounded 141
- severance 71
- integrity 259
- Astride 68
- flimsy 179
- subordination 72
- density 524
- incarnation 332
- ending 475
- within 520
- disorderly 106
- crabs 46
- eastern 450
- wonderingly 57
- Vampire 111
- boiler 90
- diving board 97
- death rattle 94
- houseboy 52
- uneducated 147
- craftsman 235
- Print 153
- liquidation 73
- boundary 510
- pastiche 92
- uncooperative 65
- educate 460
- Gallup poll 69
- acute 468
- vertigo 74
- Exploration 227
- Pop 209
- aircraft 539
- Square Mile 85
- mal- 80
- Drowsy 184
- symbol 563
- disclaim 114
- scan 554
- lateness 86
- migrate 257
- disinter 153
- Injury 221
- lowlight 73
- finish with 97
- bolt 459
- standoffish 100
- rhetorician 73
- statesman 543
- long-distance 116
- ascend 251
- conceptualise 123
- interdict 57
- merger 183
- supersize 64
- freewill 69
- Appraisal 191
- sap 347
- dilatory 113
- Muḥammad 51
- fuss over 97
- kind of 95
- kin 152
- dew 521
- readability 52
- Polished 157
- boob tube 87
- consolation 123
- light 404
- atomic energy 37
- hanging 176
- Much 175
- city editor 78
- memoir 204
- enormousness 655
- speaker 542
- refuse 571
- intricacy 132
- Paragraph 247
- Trick 175
- megapixel 49
- immature 74
- word 327
- agent 572
- Obsolete 203
- come around 89
- pugnacious 77
- feign 199
- consolidate 205
- poetic 138
- countryside 199
- Daylight 159
- agony aunt 106
- Clue 211
- obituary 98
- lift 576
- Fireproof 28
- pushy 121
- fussy 291
- plebeian 66
- laughter 507
- Metals 48
- baptize 119
- roughneck 198
- agm 118
- stanchion 74
- analogy 155
- prelim 42
- conjugation 105
- fourth dimension 79
- Transpose 35
- bewildering 302
- hair-trigger 96
- statistic 235
- Remain 194
- messiah 79
- Valuable 208
- Vessel 204
- eat 272
- nuisance 497
- trilogy 146
- postmodernism 42
- PRECLUDE 94
- impractical 224
- Ghost 136
- commence 225
- personality 478
- atmospheric 403
- Consumption 205
- treasury 346
- mirror 517
- military 501
- herder 80
- wa 99
- ideological 182
- Subjects of study 2
- eater 193
- graphic 211
- unorthodox 251
- benevolence 116
- riverbank 55
- integer 94
- for the duration 16
- Utilization 93
- phoneme 64
- prophesy 112
- colt 212
- Amusing 206
- effective 510
- granular 108
- hope 316
- exploration 196
- blacklegging 29
- Pundit 178
- gauze 188
- blindside 130
- -ify 137
- ginseng 110
- legacy 219
- avowal 114
- ethic 222
- sketchbook 60
- piecework 80
- soprano 104
- spectral 108
- indecipherable 238
- doubtless 476
- illuminate 223
- paste 543
- Editorial 122
- bedroom 228
- ground ball 90
- detractor 88
- syracuse 55
- air strike 131
- penalty 326
- fire 310
- conservation area 64
- appoint 502
- eyewear 102
- AFTER 63
- stickpin 101
- respectively 458
- jumps 58
- focal 108
- lsd 83
- scathe 73
- doorstep 127
- imperialism 130
- ultrasound 221
- steadfast 116
- aerialist 50
- Agency 242
- anthropomorphism 105
- canny 140
- Partake 64
- simultaneous 253
- flypast 85
- disregard 297
- Sabotage 203
- Aberration 21
- crest 145
- telephony 65
- harlotry 42
- home 344
- Primus 50
- undo 550
- leach 196
- photosynthesis 110
- helm 175
- expendable 119
- Extinct 99
- lady 481
- entropy 107
- Supposed 138
- homograph 156
- mobbing 34
- externals 76
- siding 176
- coupon 227
- dressy 141
- luvvies 33
- darling 476
- particular 467
- specially 445
- doughty 132
- success 638
- engineer 505
- magpie 67
- faculty 528
- spice 149
- gross domestic product 88
- Profound 60
- favorable 550
- unfortunately 446
- parlous 73
- exit 547
- innocuous 82
- mockery 162
- Jewish 356
- crisp 283
- theorist 69
- Dawn 197
- hereabouts 67
- crease 285
- Genome 75
- mottled 190
- ventilate 249
- fast-breeder 49
- Slander 133
- fishery 110
- massively 48
- Despicable 112
- monitor 566
- basalt 115
- spry 88
- shepherdess 53
- navigation 513
- fold 456
- elongated 82
- insignia 135
- kaleidoscope 78
- Scent 169
- orator 69
- videophone 55
- off and on 26
- instrumental 202
- fake 168
- rapper 123
- variegate 41
- exclamation 135
- beatboxing 41
- reference 678
- cherub 142
- Boundless 118
- reasonable 458
- titlist 62
- guitar 181
- Upper 107
- grotto 108
- senseless 93
- potion 78
- conceptually 134
- -rd 48
- weepy 107
- hmm 78
- Scale 250
- Spam 13
- Ton 231
- Gauge 105
- beggar 426
- Retrospective 55
- meager 107
- sad 280
- chemise 86
- underrepresented 42
- Scarce 183
- parodied 40
- amplification 117
- headstrong 204
- shutter 241
- Reasons 75
- pharmacies 31
- news 366
- Fairy 117
- Strategically 64
- tam 42
- adulate 51
- distributor 135
- computation 121
- follow on 113
- indication 636
- enamoured 56
- extroversion 93
- grown-up 225
- prison 520
- nother 59
- rpm 62
- Broth 78
- holdover 146
- championship 263
- cottage 510
- Adjective 84
- TRANSMIT 105
- Advisory 107
- bountiful 74
- imperative 206
- vaccinate 206
- goon 211
- participant 272
- valuables 104
- chafe 111
- soak 508
- Nazi 88
- Web 211
- impart 126
- disfigure 125
- Livable 176
- mouthier 39
- fade 651
- japanner 26
- conversation 235
- pauper 85
- reelect 108
- wolf 525
- hullo 46
- Argument 245
- frankfurter 91
- nowadays 462
- bean 480
- superfluous 196
- comprehension 556
- Boom 227
- nip 175
- Salvation 91
- Captivity 39
- backwoods 90
- landless 131
- deflection 93
- Lift 330
- Preserve 163
- versus 255
- Spatula 119
- black 230
- displeasure 131
- passenger 515
- ropeable 36
- persevering 141
- creep 525
- double bill 91
- catsup 114
- Chalk 142
- threadbare 250
- Specious 21
- ahoy 110
- anecdote 171
- theater 266
- residuary 43
- revulsion 391
- Reiterate 150
- thousandfold 35
- imagination 528
- symbolize 226
- reconstructionist 37
- moreover 435
- truth 485
- muddy 534
- Cure 236
- collective 477
- play at 45
- BIODEGRADABLE 84
- café 438
- beekeeping 72
- twentieth 66
- kelvin 44
- yoghurt 32
- Pulp 88
- Exceed 116
- fidelities 39
- reportedly 123
- percolation 34
- nonentity 62
- off-white 72
- EFFORT 66
- Exposed 189
- rust 537
- swoony 37
- cheese 496
- institutions 70
- stubbled 40
- Differential 167
- Opposite 288
- leukemia 235
- saw 448
- interception 72
- weighty 93
- defeatism 117
- hafnium 76
- pm 197
- Humerus 192
- dud 132
- decide 281
- Cpl. 54
- unbeknown 46
- revoke 87
- opportunely 66
- mug 503
- e-tail 117
- executive order 99
- prebake 38
- tableau 78
- intellectual 486
- intend 588
- whammy 87
- Circuit 241
- traitor 506
- Riot 127
- suave 109
- inadvertency 39
- maigre 64
- dump truck 99
- Lawyer 52
- dildo 106
- reason 360
- gossipy 161
- Duration 107
- jordan 47
- hypocritical 125
- predict 537
- stubble 57
- Landfill 41
- catastrophic 166
- Gaze 20
- caring 119
- purchase 543
- trampoline 217
- SINO 42
- moth 130
- swordsman 66
- interview 509
- Zeal 127
- after 212
- dap 37
- prepare 558
- soft goods 41
- doula 120
- maintain 521
- balky 133
- Foil 11
- Desert 200
- mimicked 25
- Guam 85
- low 309
- Subvert 81
- minstrel 65
- Nestle 198
- dickey 81
- bouncer 95
- utterly 281
- recommendation 532
- intra 38
- amenable 214
- bacillus 150
substance
2 ENTRIES FOUND:
plural substances
plural substances
Learner's definition of SUBSTANCE
1
[count]
a : a material of a particular kind物质；物品
- chemical/toxic/hazardous/dangerous substances化学/有毒/有害/危险物质
- The pancreas secretes a substance called insulin.胰腺分泌一种叫胰岛素的物质。
- The floor was covered with a white, powdery substance that turned out to be flour.地板上撒满的白色粉末状物质原来是面粉。
b : a drug that is considered harmful and whose use is controlled by law or made illegal（有害）药物
- heroin and other illegal substances海洛因和其他非法药物
- He had a history of substance abuse.他有嗜毒史。
- Codeine is a controlled substance. [=a drug that you need permission from a doctor to use]可待因是一种管制药物。
2
[noncount]
a : the quality of being meaningful, useful, or important实质；真正的意义；内涵
- matters of substance实质性问题
- When has he ever said anything of substance?他什么时候说过任何有意义的话？
- The book lacks substance.这本书内容空洞。
b : the quality of being true or believable真实性；可信性
- These rumors have no substance. = These rumors are without substance. [=these rumors are not true]这些谣言没有可信度。
- The results of the study give substance to their theory.研究成果证明了他们理论的正确性。
3
[noncount] : the most basic or necessary part or quality of something : essence主旨；要义
- the substance of my argument本人论点的要义
- These two books differ in both style and substance. [=content]这两本书在风格和内容上都截然不同。
- He stated, in substance [=in essence, essentially], that it is not his fault and he will not pay for damages.他所说的中心意思就是，这并不是他的错，他也不会赔偿任何损失。
a man/woman/person of substance
literary : a person who is rich and powerful有钱有势的人
- She married a man of substance.她嫁给了一个有钱有势的大人物。
sum and substance
substance
noun
sub·stance ˈsəb-stən(t)s 
1
a
: essential nature : essence
b
: a fundamental or characteristic part or quality
c
Christian Science : god sense 1b
2
a
: ultimate reality that underlies all outward manifestations and change
b
: practical importance : meaning, usefulness
Synonyms
Example Sentences
The pancreas secretes a substance called insulin. The floor was covered with a white, powdery substance that turned out to be flour. heroin and other illegal substances He had a history of substance abuse. When has he ever said anything of substance? The results of the study give substance to their theory. the substance of my argument See More
Recent Examples on the Web The county also promised to establish 300 additional substance use and mental health beds, according to a copy of the term sheet. 
Benjamin Oreskes, Los Angeles Times, 12 Sep. 2022 Her mother, Crystal Sorey, and father had substance abuse issues, the agency said. Marlene Lenthang, NBC News, 9 Sep. 2022 At the same time, the voices of both people who use drugs and people with substance-use disorders are absent from the chapter. Melissa Gira Grant, The New Republic, 6 Sep. 2022 One doctor who signed the letter, Stephanie Pierce, is the medical director of a clinic for pregnant women with substance-use disorders at the University of Oklahoma Health Sciences Center. Cary Aspinwall, al, 1 Sep. 2022 One doctor who signed the letter, Stephanie Pierce, is the medical director of a clinic for pregnant women with substance-use disorders at the University of Oklahoma Health Sciences Center. Amy Yurkanin, Washington Post, 1 Sep. 2022 However, the resident says Clenney’s substance use caused her demeanor to change. Andrea Marks, Rolling Stone, 26 Aug. 2022 According to a 2020 report from the homeless services agency, more than 14,000 unhoused people in the county have serious mental illnesses and more than 15,000 are grappling with substance abuse issues. Nick Watt, CNN, 24 Aug. 2022 Provost cited Renfro’s fear of them, substance abuse issues and a difficult childhood involving an alcoholic parent, an ADHD diagnosis at the age of 5, and exposure to domestic violence. Zaz Hollander, Anchorage Daily News, 18 Aug. 2022 See More
Benjamin Oreskes, Los Angeles Times, 12 Sep. 2022 Her mother, Crystal Sorey, and father had substance abuse issues, the agency said. Marlene Lenthang, NBC News, 9 Sep. 2022 At the same time, the voices of both people who use drugs and people with substance-use disorders are absent from the chapter. Melissa Gira Grant, The New Republic, 6 Sep. 2022 One doctor who signed the letter, Stephanie Pierce, is the medical director of a clinic for pregnant women with substance-use disorders at the University of Oklahoma Health Sciences Center. Cary Aspinwall, al, 1 Sep. 2022 One doctor who signed the letter, Stephanie Pierce, is the medical director of a clinic for pregnant women with substance-use disorders at the University of Oklahoma Health Sciences Center. Amy Yurkanin, Washington Post, 1 Sep. 2022 However, the resident says Clenney’s substance use caused her demeanor to change. Andrea Marks, Rolling Stone, 26 Aug. 2022 According to a 2020 report from the homeless services agency, more than 14,000 unhoused people in the county have serious mental illnesses and more than 15,000 are grappling with substance abuse issues. Nick Watt, CNN, 24 Aug. 2022 Provost cited Renfro’s fear of them, substance abuse issues and a difficult childhood involving an alcoholic parent, an ADHD diagnosis at the age of 5, and exposure to domestic violence. Zaz Hollander, Anchorage Daily News, 18 Aug. 2022 See More Word History
Etymology
Middle English, from Anglo-French, from Latin substantia, from substant-, substans, present participle of substare to stand under, from sub- + stare to stand — more at stand
First Known Use
14th century, in the meaning defined at sense 1a
Time Traveler
The first known use of substance was in the 14th century Phrases Containing substance
noun¹
noun²
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