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substance

noun

sub·​stance ˈsəb-stən(t)s How to pronounce substance (audio)
1
a
: essential nature : essence
b
: a fundamental or characteristic part or quality
c
Christian Science : god sense 1b
2
a
: ultimate reality that underlies all outward manifestations and change
b
: practical importance : meaning, usefulness
the … bill—which will be without substance in the sense that it will authorize nothing more than a set of ideas Richard Reeves
3
a
: physical material from which something is made or which has discrete existence
b
: matter of particular or definite chemical constitution
c
: something (such as drugs or alcoholic beverages) deemed harmful and usually subject to legal restriction
possession of a controlled substance
substance abuse
4
: material possessions : property
a family of substance
substanceless
ˈsəb-stən(t)s-ləs How to pronounce substance (audio)
adjective
Phrases
in substance
: in respect to essentials : fundamentally

Synonyms

Example Sentences

The pancreas secretes a substance called insulin. The floor was covered with a white, powdery substance that turned out to be flour. heroin and other illegal substances He had a history of substance abuse. When has he ever said anything of substance? The results of the study give substance to their theory. the substance of my argument See More
Recent Examples on the Web The county also promised to establish 300 additional substance use and mental health beds, according to a copy of the term sheet. Benjamin Oreskes, Los Angeles Times, 12 Sep. 2022 Her mother, Crystal Sorey, and father had substance abuse issues, the agency said. Marlene Lenthang, NBC News, 9 Sep. 2022 At the same time, the voices of both people who use drugs and people with substance-use disorders are absent from the chapter. Melissa Gira Grant, The New Republic, 6 Sep. 2022 One doctor who signed the letter, Stephanie Pierce, is the medical director of a clinic for pregnant women with substance-use disorders at the University of Oklahoma Health Sciences Center. Cary Aspinwall, al, 1 Sep. 2022 One doctor who signed the letter, Stephanie Pierce, is the medical director of a clinic for pregnant women with substance-use disorders at the University of Oklahoma Health Sciences Center. Amy Yurkanin, Washington Post, 1 Sep. 2022 However, the resident says Clenney’s substance use caused her demeanor to change. Andrea Marks, Rolling Stone, 26 Aug. 2022 According to a 2020 report from the homeless services agency, more than 14,000 unhoused people in the county have serious mental illnesses and more than 15,000 are grappling with substance abuse issues. Nick Watt, CNN, 24 Aug. 2022 Provost cited Renfro’s fear of them, substance abuse issues and a difficult childhood involving an alcoholic parent, an ADHD diagnosis at the age of 5, and exposure to domestic violence. Zaz Hollander, Anchorage Daily News, 18 Aug. 2022 See More

Word History

Etymology

Middle English, from Anglo-French, from Latin substantia, from substant-, substans, present participle of substare to stand under, from sub- + stare to stand — more at stand

First Known Use

14th century, in the meaning defined at sense 1a

Time Traveler
The first known use of substance was in the 14th century

Phrases Containing substance

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