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: a primary sore or ulcer at the site of entry of a pathogen (as in tularemia)
especially : the initial lesion of syphilis
Example Sentences
Recent Examples on the Web Sometimes syphilis presents as a painless chancre, or a round, open sore on your genitals. 
Zahra Barnes, SELF, 12 Oct. 2021 Syphilis is transmitted from person to person by direct contact with a syphilitic sore, known as a chancre. Gabriela Miranda, USA TODAY, 16 June 2021 Syphilis: If your partner has chancres (firm, round sores) that aren’t covered by the condom, the infection can spread to you. Zahra Barnes, SELF, 29 Aug. 2019 In the primary stage, chancres (usually firm, round, and painless) appear at the site of infection. Carolyn L. Todd, SELF, 28 May 2019
Zahra Barnes, SELF, 12 Oct. 2021 Syphilis is transmitted from person to person by direct contact with a syphilitic sore, known as a chancre. Gabriela Miranda, USA TODAY, 16 June 2021 Syphilis: If your partner has chancres (firm, round sores) that aren’t covered by the condom, the infection can spread to you. Zahra Barnes, SELF, 29 Aug. 2019 In the primary stage, chancres (usually firm, round, and painless) appear at the site of infection. Carolyn L. Todd, SELF, 28 May 2019 Word History
Etymology
French, from Old French, from Latin cancer
First Known Use
1585, in the meaning defined above
Time Traveler
The first known use of chancre was in 1585 Phrases Containing chancre
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