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opiate

1 of 2

noun

opi·​ate ˈō-pē-ət How to pronounce opiate (audio) -ˌāt How to pronounce opiate (audio)
plural opiates
1
a
: an alkaloid drug (such as morphine or codeine) that contains or is derived from opium, binds to cell receptors primarily of the central nervous system and gastrointestinal tract, acts to block pain, induce sedation or sleep, depress respiration, and produce calmness or euphoria, and is associated with physiological tolerance (see tolerance sense 4a(1)), physical and psychological dependence, and addiction upon repeated or prolonged use
b
: a synthetic or semisynthetic drug (such as fentanyl or methadone) or an endogenous substance (such as beta-endorphin) that binds to opiate cell receptors and produces physiological effects like those of opium derivatives: opioid sense 1
… fentanyl, a synthetic opiate that is 90-100 times more potent than morphine. The Economist
Current peptide research has uncovered at least two groups of endogenous opiates in the CNS that modulate the perception of pain. Nicholas T. Zervas

Note: The use of opiate for substances that bind to opiate receptors but are not opium derivatives is often considered technically incorrect. Such substances are more commonly referred to as opioids. The word opioid itself was originally used only for these substances, but it has now become widely accepted as a broader term encompassing any substance—natural, synthetic, opium-derived or not—that binds to opiate receptors and has morphine-like activity.

2
: something likened to a drug that induces rest or inaction or quiets uneasiness
Operatic music is an opiate that lowers our critical guard and allows us to entertain views that our good liberal selves would disavow were they presented in naked prose. Paul Robinson
… the novel's real drug is the opiate of nostalgia. Richard, narrating the events at a distance of ten years, is still too in love with the friends to look at them with an even faintly critical eye. Ruth Franklin

opiate

2 of 2

adjective

1
a
: containing or mixed with opium
b
: of, relating to, binding, or being an opiate
opiate receptors
2
a
: inducing sleep : narcotic
b
: causing dullness or inaction

Synonyms

Noun

Adjective

Example Sentences

Noun Many see television as an opiate of the masses. a cultural critic who argues that the Internet has now joined television as an opiate of the American people Adjective morphine is an opiate drug
Recent Examples on the Web
Noun
The Commerce Department said sales to Russia of the powerful opiate will now require a U.S. government license. Jeanne Whalen, Washington Post, 15 Sep. 2022 The counterfeit pills often contain fentanyl, a synthetic opiate that is deadly in doses as small as 2 milligrams. Kelly Meyerhofer, Journal Sentinel, 24 Aug. 2022 The synthetic opiate is 80 to 100 times stronger than morphine, and is especially deadly because it is pressed into pills made to look like Xanax, Adderall or Oxycodone, or mixed into other drugs. Celina Tebor, USA TODAY, 13 July 2022 That includes methadone, Suboxone and Kadian, long-acting opioids that satiate the craving for an opiate without providing the high. New York Times, 26 July 2022 Fentanyl, which is a synthetic opiate, is 80 to 100 times stronger than morphine. Mike Snider, USA TODAY, 15 July 2022 The San Diego County Sheriff’s Department has started the process of installing boxes of naloxone, a life-saving medication that can reverse an opiate overdose, in communal areas in all six of its jails. San Diego Union-Tribune, 15 June 2022 For decades, the country has been a global hub for opium production, estimated to supply 80 percent of the world’s opiate users. Washington Post, 2 May 2022 One is that profit is itself a powerful opiate that can blind corporate leaders to the consequences of their actions. David Meyer, Fortune, 31 May 2022
Adjective
The story addresses the traumatic after effects of the Vietnam War, LGBTQ and racial issues, domestic abuse, opiate addiction and illiteracy, as well as the experience of agricultural workers in the Connecticut Shade Tobacco fields in Windsor. Susan Dunne, Hartford Courant, 17 Aug. 2022 The case also underscored the dangers of unmonitored opiate withdrawal. Kelly Davis, San Diego Union-Tribune, 20 June 2022 Though psychedelics like psilocybin and ibogaine were first researched in the 1950s for alcohol abuse and opiate addiction treatment, today, drugs like MDMA, ketamine, and LSD have been added to a growing body of research. Manee Magee, SELF, 21 July 2022 The new filings also argue the Sheriff’s Department has failed to enact policies and procedures to address the high rate of opiate overdoses, particularly fentanyl, in its jails. Kelly Davis, San Diego Union-Tribune, 2 May 2022 Yet another misconception, according to Malacara, is that ibogaine is only useful for people who are struggling with opiate use. Amanda Siebert, Forbes, 16 May 2022 Current and former inmates have told The San Diego Union-Tribune that people turn to smuggled drugs to offset the side effects of opiate withdrawal, which can last for days and include vomiting, seizures and muscle pain. Kelly Davis, San Diego Union-Tribune, 11 May 2022 The country already had some of the highest rates of opiate addiction in the world, according to the latest U.N. data. Washington Post, 2 May 2022 Quitting with the use of opiate antagonists, hot yoga, and nonalcoholic tequila seems every bit as righteous—and evidently more effective—than sweating it out in the rooms. Virginia Heffernan, Wired, 19 Apr. 2022 See More

Word History

Etymology

Noun

Middle English, borrowed from Middle French & Medieval Latin; Middle French, borrowed from Medieval Latin opiātum, from Latin opium opium + -ātum -ate entry 1

Adjective

borrowed from Medieval Latin opiātus "soporific," from Latin opium opium + -ātus -ate entry 3

First Known Use

Noun

15th century, in the meaning defined at sense 1a

Adjective

1543, in the meaning defined at sense 1a

Time Traveler
The first known use of opiate was in the 15th century

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