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acetaminophen

noun

acet·​amin·​o·​phen ə-ˌsē-tə-ˈmi-nə-fən How to pronounce acetaminophen (audio)
ˌa-sə-tə-
: a crystalline compound C8H9NO2 that is a hydroxy derivative of acetanilide and is used in chemical synthesis and in medicine to relieve pain and fever

Example Sentences

Recent Examples on the Web The National Kidney Foundation recommends acetaminophen, the active ingredient in TYLENOL®, as the pain reliever of choice for occasional use in patients that have underlying kidney disease. Noel Cody, Essence, 2 Aug. 2022 Further, Sun Pharma also recalled about 34,660 units of Kroger brand acetaminophen. Haley Yamada, ABC News, 16 June 2022 Long before the current opioid crisis, the scientific community and literature knew of the dangers of NSAIDs and acetaminophen (Tylenol). Scientific American, 1 Mar. 2022 Percocet, a combination of acetaminophen and oxycodone, was discovered in Skaggs’ hotel room, but it wasn’t discovered in his system, according to the autopsy report. Los Angeles Times, 15 Feb. 2022 Tylenol contains the active ingredient acetaminophen, and Advil contains the active ingredient ibuprofen. Serena Coady, SELF, 12 Feb. 2022 Percocet, an opioid, is a mixture of oxycodone and acetaminophen. Los Angeles Times, 14 Feb. 2022 The aspirin and acetaminophen tablets are still good to use. Chris Smith, BGR, 31 Jan. 2022 Fewer patients in the treatment group reported taking acetaminophen (Tylenol), but that was true even in the first week of the study, when the treatment and control groups were reporting practically identical levels of pain. Paul T. Von Hippel, STAT, 24 Jan. 2022 See More

Word History

Etymology

acet(yl) + amino + phen(ol)

Note: Shortened from N-acetyl-p-aminophenol. Acetaminophen was introduced as a generic name roughly coincident with the introduction of the trademark preparation Tylenol, which was first marketed as "Children's Tylenol Elixir" in 1955 by McNeil Laboratories. Synthesis of the substance, as acetylamidophenol, was first reported in Berichte der Deutschen Chemischen Gesellschaft, 11. Jahrgang (Jan.-Juni, 1878), p. 232-33 (H. N. Morse, "Ueber eine neue Darstellungsmethode der Acetylamidophenole"). Its antipyretic properties were recognized by the German physician Josef von Mering in the 1893 article "Beiträge zur Kenntniss der Antipyretica" (Therapeutische Monatshefte, 7, pp. 577-87)—he also refers to it as acetylamidophenol.

First Known Use

1958, in the meaning defined above

Time Traveler
The first known use of acetaminophen was in 1958

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