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naloxone

noun

nal·​ox·​one na-ˈläk-ˌsōn How to pronounce naloxone (audio)
: a synthetic potent antagonist of narcotic drugs (such as morphine and fentanyl) that is administered especially in the form of its hydrochloride C19H21NO4·HCl

Note: Naloxone is administered by injection or as a nasal spray to reverse the effects of opioids especially in the emergency treatment of opioid overdose. It is also administered in combination with buprenorphine in the form of a dissolvable tablet placed under the tongue or a film placed inside the cheek to treat opioid dependence.

Example Sentences

Recent Examples on the Web The manager listened to Piccolo's instructions on how to use Narcan, the brand name of the drug naloxone, and added four boxes of the nasal spray to the hotel's first-aid kit. Katheryn Houghton, CNN, 15 Aug. 2022 Community events at which naloxone is distributed are also on the rise, Dr. Vakharia says. Maggie O'neill, SELF, 25 Aug. 2022 Researchers found that there is no state with enough naloxone to meet demand, even as drug overdoses have surged to a record high. Meryl Kornfield, Anchorage Daily News, 7 Aug. 2022 The Anchorage Police Department doesn’t require officers to carry or administer naloxone, a policy that hasn’t changed even as overdose deaths in the Anchorage area have nearly tripled since 2018. Annie Berman, Anchorage Daily News, 4 Aug. 2022 But research has consistently shown that naloxone and needle exchanges save lives and reduce the transmission of HIV and hepatitis. Joanna Slater, Washington Post, 5 Aug. 2022 What's more, people in isolation were more likely to use drugs alone, Houry said, without a bystander present to call 911 in case of emergency or administer naloxone, which can reverse opioid overdoses. Erika Edwards, NBC News, 19 July 2022 Emergency personnel used naloxone, or Narcan, to resuscitate the teens, one of whom suffered a brain injury, said Dr. Siddarth Puri, the associate medical director of prevention with the county health department. Felicia Alvarez, Los Angeles Times, 2 June 2022 Installing naloxone boxes are part of a larger effort the department launched this month to better identify and treat people struggling with substance abuse. San Diego Union-Tribune, 15 June 2022 See More

Word History

Etymology

N-allyl + hydroxy- + -one

First Known Use

1964, in the meaning defined above

Time Traveler
The first known use of naloxone was in 1964

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